How to Determine Whether a Disease Is Suitable for MSC Treatment?

Mesenchymal stem cells (MSC) are a type of stem cell with a very wide range of applications. There is no other type of stem cell. This is because mesenchymal stem cells themselves have low immunogenicity, are easy to be cultured on a large scale, can be used allogeneically, and are suitable for treating a variety of diseases. .

The reason for writing this article is that I saw some cell companies using mesenchymal stem cells to treat many very difficult to treat diseases without considering the limitations of the functions of mesenchymal stem cells themselves. The root cause is that the understanding of mesenchymal stem cells is not deep enough. . The consequence of this is that satisfactory clinical efficacy is often not achieved, which leads to negative evaluation of mesenchymal stem cells. To put it simply, I don’t know how to use mesenchymal stem cells well, but blame the mesenchymal stem cells for their ineffectiveness.

Which diseases mesenchymal stem cells can treat depends on the functions of the mesenchymal stem cells themselves. Mesenchymal stem cells have many functional properties, but their therapeutic functions are nothing more than four: ① immune regulation, ② eliminating inflammation, ③ supporting hematopoiesis, and ④ promoting repair. Therefore, if the pathological characteristics of the disease are consistent with these four points, treatment with mesenchymal stem cells can often achieve good results.

It should be noted that the fourth point is that whether the function of promoting repair can be displayed depends on the regeneration ability of tissues and organs. If the regeneration ability of a tissue or organ is very weak, such as lungs, kidneys, heart, nerve cells, etc., then the effect of treatment with mesenchymal stem cells (MSC) will not be that significant, although it will still be better than current conventional treatments. a lot of.

For refractory diseases, comprehensive treatment is often required to achieve amazing results, and mesenchymal stem cells cannot be relied upon as a single treatment method. Moreover, the best treatment options for mesenchymal stem cells to treat many diseases are still being explored and optimized. Remember: Mesenchymal stem cells cannot be regarded as the last life-saving straw, nor can they be glorified as a magic water that can cure all diseases.